Wednesday, 29 June, 2022

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STI12 MPCR-ULFA Kit

Overview of STI12 

There are currently more than 100 known genotypes of the human papillomavirus (HPV) associated with a number of diseases that include many types of cancers, in particular cervical cancer. The types of HPV are often called high-risk and low-risk, based on whether they put a person at risk for cancer. Two types of HPV (16 and 18) cause 70% of cervical cancers and precancerous lesions of the cervix.

Therefore, sensitive and specific detection of HPV in cervical samples is a useful tool for the early diagnosis of epithelial neoplasms and anogenital lesions. The PaxView STI12 MPCR-ULFA kit is designed for the simultaneous detection of two types of high risk (16, 18) and common positive of HPV by means of the multiplex polymerase chain reaction (MPCR) and the subsequent assay patented universal lateral flow (ULFA) based on DNA-DNA hybridization on nitrocellulose membranes.

Objectives

HPV16, 18, common positive

Specimens

Vaginal/cervical swab, urine

Product storage

  • PaxView DNA Extraction Kit: – 2 ~ 8 ℃ Storage
  • PaxView HPV16 / 18 / Other MPCR Kit: – Storage at -25 ~ -15 ℃
  • PaxView ULFA Kit: – 15 ~ 30 ℃ Storage

Features and Benefits

  • Visually verify the test result on the ULFA device
  • Simultaneously detects high-risk HPV (16 and 18) and common positive in one assay
  • Fast and highly sensitive detection (within 10 min)

Performances

  1. DNA extraction: 15 min
  2. DNA amplification: 2 hours
  3. ULFA detection: 10 min